Impotence Treatment and Popular Sildenafil UK Synthetic Drug

Sildenafil (compound UK-92,480) has come to be known as the little blue pill that saved the world. It is commonly known as Viagra, which is one of its most popular brand names. This article focuses on the use of Sildenafil in impotence treatment. 

Impotence, also known as erectile dysfunction, is the inability to get and sustain a satisfactory erection to complete sexual intercourse. It is a very common condition in men, and its probability increases with age. It has a range of causes, both physical and psychological.

Physical causes include hormonal problems, injury, or narrowing of blood vessels going to the penis. Psychological causes include anxiety, depression, or even relationship problems. Treating impotence depends on what has caused it. 


It was synthesized by a group of pharmaceutical chemists working at a research facility in the UK. It was, at first, intended to be used in treating hypertension and angina pectoris. Clinical trials showed it to have little effect on angina but could instead induce penile erections. It was thereafter marketed for erectile dysfunction.

How Sildenafil UK Synthetic Drug works in Treating impotence

It acts by blocking PDE5, an enzyme found in various tissues, which promotes the breakdown of cGMP, which regulates blood flow in the penis. This, therefore, enables an increase in blood flow, enabling erection. The subject must, however, be sexually aroused for this to work.

It is usually taken orally for impotence treatment. Its onset is around 20 minutes and lasts for approximately two hours.

Side effects

The most common side effects include dizziness, headache, flushing, or stomach upset. You could also experience: 

  • Vision impairments, including blurred vision, increased sensitivity to light, or decreased vision.
  • Loss or decrease in hearing  
  • A painful or prolonged erection. This could result in the penis being damaged.

Do not hesitate to seek medical help if you experience the symptoms above or any others that you are uncertain of.

Food and alcohol interaction

Alcohol use can contribute further to lowering blood pressure which could already be lowered by Sildenafil. It is therefore advised to limit alcohol consumption while using the drug. It is also wise to decrease the amount of grapefruit in your diet while taking the drug. Grapefruit is known to increase the levels of Sildenafil in your body hence delaying the time it will take for the medication to work. 

Drug interaction

Drugs that interfere with the metabolism of Sildenafil include erythromycin, cimetidine, and protease inhibitors for the treatment of HIV infection. Care should be taken while under these medications.


Viagra is very effective in treating impotence. This has given more men the courage to come forward and be diagnosed with the condition. In countries such as the UK, however, it is available over the counter, which has made it prone to misuse. 

Music Genres

Top Ten Best Music Genres

A music genre is a category which identifies certain pieces of music as part of a shared tradition or collection of conventions. Music can be categorized into different genres in several different ways. Music is an art form, which means that these classifications and divisions are often subjective and controversial, with some genres overlapping with others.

Here is the top 10 genres in the music industry are as follows.

Electronic Dance Music

Usually referred to as EDM, this form of music is created by DJs who add dozens of tunes to a piece creating unique musical notes and sounds. It is typically played in clubs or live events, depending on your accessibility for the same. In the early days of the genre, electronic dance music was in the form of Jamaican dub music which proceeded to become the electronic music of Kraftwerk eventually transforming into the disco music of the Yellow Magic Orchestra, Giorgio Moroder and many more.

Rock Music

Originating as Rock & Roll in the United States, rock music has been taking the world by storm since the 1950s. It is a style of music that actually began around string instruments, but in the current scenario where other modern instruments are also being used, it is becoming a little challenging to give it a proper definition. Its strong and loud beats make it popular among the youth. Some of the rock stars who popularized the rock culture include Nirvana, Pink Floyd, Metallica, The Doors, Megadeth and Queen.

Rock Music


Jazz has its roots both in West African as well as in European culture. Identified with swing and blue notes, it is generally considered that Jazz is one of America’s original art forms and has a unique combination of creativity, interactivity and coactions. Starting in the late 19th and early 20th century, Jazz has paved the way for introducing the world to a number of women musicians and performers such as Betty Carter, Ella Fitzgerald, Abbey Lincoln and Ethel Waters.



Using electronic instruments attracts music lovers for its deep bass and unusual rhythm, dubstep can be seen as a subset of the electronic music genre. People often consider dubstep to be a darker form of music, but this genre has successfully secured its place in the industry since its birth in the late 1990s.

Rhythm and Blues

Vocalists such as Mariah Carey, Beyoncé, Rihanna, Usher and even the legendary Michael Jackson have all made it big in the music industry with their love for this type of music. The African-American style of music which originated in the 1940s is a combination of hip hop, pop, dance, soul and funk focusing on themes such as relationships, freedom and sex.


Techno music is hard to miss during clubbing nowadays, but it is Detroit techno that is generally considered to be the foundation of this form of music. The use of technology today has dramatically enhanced the quality and versatility of techno style music, unlike the time of its inception and popularizing it among the people.